Applied Sciences > Medicine > N-007

Research Title Extraction, Characterization and Bio-Assay for Larvicidal Activity of Some Philippine Medicinal Plants
Research Personnel Leader:
Dr. Rosalinda C. Torres

Research Duration Start:
16 April 2012
15 April 2015
Research Location Palawan, Davao, Tarlac, etc.
Research Description Dengue hemorrhagic fever continues to be a leading cause of morbidity and mortality attaining epidemic proportions in several regions of the country especially the National Capital Region. Treatment is mainly supportive as there is no specific therapy available to date. Our main focus is now on the development of vector control measures that are acceptable to the populace, cost-effective, and more importantly safe for the environment. The use of natural alternatives such as essential oils and plant extracts can provide the best option as environmentally safe natural anti-larvicides.
Research Objectives (1) To undertake crude extraction and extract essential oils from some Philippine medicinal plants; (2) To determine the larvicidal activity of the crude extracts and essential oils; (3) To undertake phytochemical screening of the crude extract; (4) To conduct polarity-based fractionation of the crude extracts and determine larvicidal efficacy of the fractions; (5) To isolate and characterize further the most active fraction of the plant which exhibited the most significant activity; (6) To analyze the essential oils for physico-chemical properties and chemical composition bychromatographic methods; (7) To develop larvicidal product(s) that can be field tested on a wider scale; (8) To conduct product analysis and shelf-life/stability testing; (9) To conduct field trial testing of the products.
Research Beneficiary(ies) General public
Research Accoplishments Identification of candidate plants to control dengue larvae; Initial screening tests. Identified larvicidal efficacy, extracted essential oils, determined chemical properties and chemical composition
Total Research Cost
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Research Budget Breakdown Year:
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Code N-007
KRA Code Poverty Reduction and Empowerment of the Poor
Priority Thrust DOST
Pressing national problems

Sector Applied Sciences
Actual Sector Anti-dengue
Related sectors Healthcare, Natural Products, Chemistry
Entry revision: January 2021