Applied Sciences > Medicine > DG CY2020 7843

Research Title Metabolomics-Driven Discovery of Antimicrobial Drug Leads from Marine Sediment-Derived Actinomycetes of Iloilo (Year 3 of 4)
Research Personnel Leader:
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Research Duration Start:
End:
3 January 2018
30 November 2018
Research Location USA
Research Description The proposal responses to the Drug Discovery and Development R&D priority area of the Department, which aims to produce to safe, effective and affordable medicine from local natural sources to address leading causes of morbidity and mortality in the country. The proposal contributes to two Budget Priorities Framework: (1) making growth inclusive by contributing to programs that will ensure the health of Filipinos, and (2) sustaining growth momentum by supporting and developing the local herbal and pharmaceutical industry.
Research Objectives Under the Drug Discovery and Development area, the project aims to discover potential compounds for further drug development, particularly antimicrobials from actinomycetes in Iloilo, in response to the need for safe, more affordable and effective treatments for multi-drug resistant infections. The project will involve R&D work, which will also serve as an avenue for training of project personnel, and the upgrade of research facilities to make a drug discovery research center in region VI.
Research Beneficiary(ies) Health care benefits to the community, pharmaceutical industries, and research community
Research Accoplishments [CY 2017] 6Ps Metrics 1. Publication - It is expected that the project will generate at least one high quality publication in local/refereed international journals. 2. Patent - Novel compounds generated in the study will be patented 3. Product - Bioactive compounds will be licensed to pharmaceutical industries for drug development 4. Product - Bioactive compounds will be licensed to pharmaceutical industries for drug development 5. People Services - Seven (7) research personnel will work on this project and will contribute to the pool of researchers in the field of microbiology, chemistry and drug discovery 6. Places and Partnerships - The project will establish a research center in Region 6 specializing in natural products from marine sources, that is equipped with advanced tools for drug discovery research
Total Research Cost ₱19,515,851.28
Research Agencies Funding:
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USA


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Code DG CY2020 7843
KRA Code
Priority Thrust DOST
R&D


Sector Applied Sciences
Actual Sector Medical Science
Related sectors Marine Biology
Entry revision: February 2021